{"id":762,"date":"2015-10-05T19:07:35","date_gmt":"2015-10-05T17:07:35","guid":{"rendered":"http:\/\/www.epischel.de\/wordpress\/?p=762"},"modified":"2015-12-22T20:35:47","modified_gmt":"2015-12-22T19:35:47","slug":"neuronen-unterscheiden-sich-in-ihrem-genom","status":"publish","type":"post","link":"https:\/\/www.epischel.de\/wordpress\/2015\/10\/neuronen-unterscheiden-sich-in-ihrem-genom\/","title":{"rendered":"Neuronen unterscheiden sich in ihrem Genom"},"content":{"rendered":"<blockquote><p>Your neurons have unexpectedly varied genomes, and each is more closely related to heart cells than to its neighbors. Why?<\/p><\/blockquote>\n<p>Quelle: <em><a href=\"http:\/\/www.theatlantic.com\/science\/archive\/2015\/10\/the-genealogy-of-your-brain\/408232\/\">Why Each Of Your Neurons Is A Beautiful And Unique Snowflake &#8211; The Atlantic<\/a><\/em><\/p>\n<p>Ein Artikel im &#8222;The Atlantic&#8220; berichtet \u00fcber Forschung zur DNA von Neuronen. Mittels moderner DNA-Sequenzierung kann die DNA einzelner Nervenzellen ermittelt und &#8222;Abstammungslinien&#8220; erstellt werden. Es stellt sich heraus, dass beispielsweise Zellen im Prefrontalen Cortex eher mit Herzzellen verwandt sind als mit den jeweiligen Nachbarzellen.<\/p>\n<p><a href=\"http:\/\/www.sciencemag.org\/content\/350\/6256\/94\">Eine Studie<\/a> hat 226 Neuronen eines Gehirns untersucht und herausgefunden, dass sie sich mindestens f\u00fcnf verschiedenen Abstammungslinien zuordnen lassen. Dies liesse sich dadurch erkl\u00e4ren, dass im Embroynalstadium, wenn nur wenige Zellen vorhanden sind, nicht eine Zelle zur &#8222;Mutter&#8220; aller Nervenzellen wird, sondern dass aus verschiedene Zellen durch Zellteilung Nerven- und andere Zelltypen werden. Dadurch k\u00f6nnte sich das Risiko f\u00fcr Hirnkrankheiten durch Gendefekte mindern.<\/p>\n<div align=\"center\">\n<p><a href=\"https:\/\/commons.wikimedia.org\/wiki\/File:PLoSBiol4.e126.Fig6fNeuron.jpg#\/media\/File:PLoSBiol4.e126.Fig6fNeuron.jpg\"><img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/upload.wikimedia.org\/wikipedia\/commons\/d\/dc\/PLoSBiol4.e126.Fig6fNeuron.jpg\" alt=\"PLoSBiol4.e126.Fig6fNeuron.jpg\" width=\"166\" height=\"145\" \/><\/a><br \/>\n\u201e<a href=\"https:\/\/commons.wikimedia.org\/wiki\/File:PLoSBiol4.e126.Fig6fNeuron.jpg#\/media\/File:PLoSBiol4.e126.Fig6fNeuron.jpg\">PLoSBiol4.e126.Fig6fNeuron<\/a>\u201c von Wei-Chung Allen Lee, Hayden Huang, Guoping Feng, Joshua R. Sanes, Emery N. Brown, Peter T. So, Elly Nedivi &#8211; Dynamic Remodeling of Dendritic Arbors in GABAergic Interneurons of Adult Visual Cortex. Lee WCA, Huang H, Feng G, Sanes JR, Brown EN, et al. PLoS Biology Vol. 4, No. 2, e29. <a class=\"extiw\" title=\"w:Digital object identifier\" href=\"\/\/en.wikipedia.org\/wiki\/Digital_object_identifier\">doi<\/a>:<a class=\"external text\" href=\"http:\/\/dx.doi.org\/10.1371%2Fjournal.pbio.0040029\" rel=\"nofollow\">10.1371\/journal.pbio.0040029<\/a>, Figure 6f, slightly altered (plus scalebar, minus letter &#8222;f&#8220;.). Lizenziert unter <a title=\"Creative Commons Attribution 2.5\" href=\"http:\/\/creativecommons.org\/licenses\/by\/2.5\">CC BY 2.5<\/a> \u00fcber <a href=\"https:\/\/commons.wikimedia.org\/wiki\/\">Wikimedia Commons<\/a>.<\/p>\n<\/div>\n<div class=\"syndication-links\"><span class=\"syn-text\">Also on \/ Auch auf:<\/span><ul class=\"relsyn\"><li><a aria-label=\"x\" class=\"u-syndication syn-link\" href=\"https:\/\/twitter.com\/erikpischel\/status\/651133185393201152\"> <span class=\"syndication-link-icon svg-x\" style=\"display: inline-block; max-width: 1rem; margin: 2px;\" aria-hidden=\"true\" aria-label=\"X\" title=\"X\" ><svg role=\"img\" viewBox=\"0 0 24 24\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><title>X<\/title><path d=\"M18.901 1.153h3.68l-8.04 9.19L24 22.846h-7.406l-5.8-7.584-6.638 7.584H.474l8.6-9.83L0 1.154h7.594l5.243 6.932ZM17.61 20.644h2.039L6.486 3.24H4.298Z\"\/><\/svg><\/span>X<\/a><\/li><li><a aria-label=\"googleplus\" class=\"u-syndication syn-link\" href=\"https:\/\/plus.google.com\/+ErikPischel\/posts\/5n2AUnzKBGV\"> googleplusgoogleplus<\/a><\/li><\/ul><\/div>","protected":false},"excerpt":{"rendered":"<p>Your neurons have unexpectedly varied genomes, and each is more closely related to heart cells than to its neighbors. Why? Quelle: Why Each Of Your Neurons Is A Beautiful And Unique Snowflake &#8211; The Atlantic Ein Artikel im &#8222;The Atlantic&#8220; berichtet \u00fcber Forschung zur DNA von Neuronen. Mittels moderner DNA-Sequenzierung kann die DNA einzelner Nervenzellen&hellip;<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"mf2_syndication":["https:\/\/twitter.com\/erikpischel\/status\/651133185393201152","https:\/\/plus.google.com\/+ErikPischel\/posts\/5n2AUnzKBGV"],"webmentions_disabled_pings":false,"webmentions_disabled":false,"footnotes":""},"categories":[4],"tags":[130,131],"series":[],"class_list":["post-762","post","type-post","status-publish","format-standard","hentry","category-medien","tag-biologie","tag-genetik","kind-"],"kind":false,"_links":{"self":[{"href":"https:\/\/www.epischel.de\/wordpress\/wp-json\/wp\/v2\/posts\/762","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.epischel.de\/wordpress\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.epischel.de\/wordpress\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.epischel.de\/wordpress\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.epischel.de\/wordpress\/wp-json\/wp\/v2\/comments?post=762"}],"version-history":[{"count":4,"href":"https:\/\/www.epischel.de\/wordpress\/wp-json\/wp\/v2\/posts\/762\/revisions"}],"predecessor-version":[{"id":771,"href":"https:\/\/www.epischel.de\/wordpress\/wp-json\/wp\/v2\/posts\/762\/revisions\/771"}],"wp:attachment":[{"href":"https:\/\/www.epischel.de\/wordpress\/wp-json\/wp\/v2\/media?parent=762"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.epischel.de\/wordpress\/wp-json\/wp\/v2\/categories?post=762"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.epischel.de\/wordpress\/wp-json\/wp\/v2\/tags?post=762"},{"taxonomy":"series","embeddable":true,"href":"https:\/\/www.epischel.de\/wordpress\/wp-json\/wp\/v2\/series?post=762"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}